刘宏
国家重点研发计划项目负责人，山东大学博士生导师、国家自然科学杰出青年基金获得者，曾任科技部863项目评审专家和国家科学技术奖评审专家。长期从事光电功能材料和生化传感器材料的研究，作为课题负责人承担了十五、十一五和十二五国家863重点项目、自然基金重大项目、面上项目等十余项国家级科研项目。在生物微纳材料、微纳生化传感器和光电功能材料等领域都取得了重要进展。近年来，在包括Adv. Mater.。 Nano Letters, ACSNano，J. Am. Chem. Soc， 等学术期刊上表SCI文章200余篇，其中影响因子大于10的近30篇，个人文章SCI总他引次数超过9000次，H因子为45。19篇文章被Web of Science 的ESI选为“过去十 年高被引用论文”,文章入选2013年中国百篇最具影响国际学术论文，应邀在Chem.Soc. Rev. 和Adv. Mater. 、Adv.Funct. Mater. 上发表相关综述性学术论文，并被列为英国皇家学会“Top1 %高被引用中国作者”。授权专利30余项，曾获得省部级科技进步一等奖。
张宇
山东大学副研究员，
耶鲁大学-山东大学联合培养博士。
曾任耶鲁大学电子工程系副研究员。具有10余年微纳加工、光电材料、器件、光电系统、生化传感研究和产品开发经验。
主持和参与美国能源部、美国自然科学基金(NSF) 、国家重点研发计划山东省重大创新工程以及半导体材料和生化传感芯片和设备产品开发的多项科研和产业化项目。
申报美国和国际专利10余项，申请国内专利30余项，获得授权10余项。在世界知名杂志上发表论文数篇30余篇，总引用300余次，学术成果在国际会议上口头报告或张贴报告20余次发表的科研技术成果多次被行业媒体期刊sem i conductor today,nanotechweb等报道。
韩琳
山东大学教授，博士生导师，山东省泰山学者特聘专家，山东 大学杰出中青年学者，齐鲁青年学者，山东省杰出青年基金获得者。 主要研究方向：聚焦新型半导体材料、器件及其光/电传感机制，集 成微纳加工技术，面向生命健康和海洋环境监测，研发新型生物传感 芯片与系统，形成了 10 余种国际先进水平的生物芯片，在齐鲁医院、 北京大学第三医院等多家医院进行了~10000 例临床样本的验证。近年来，以第一或通讯作 者在 Chemical Society Review、Advanced Materials、Advanced Functional Materials、ACS Nano 等国际知名期刊发表学术论文 100 余篇，授权专利 70 余项，实现了 1000 万元的技术 成果转化，相关成果被中央人民广播电台特别报道。主持国家重点研发计划（课题 2 项，子 课题 1 项）、国家自然基金青年/面上、山东省杰出青年基金、山东省重大创新工程项目课 题等 10 余项，担任山东大学青年交叉科学群体项目首席。曾获山东省技术发明一等奖（第 一位）、山东省科技进步二等奖（第三位）、国际发明展览会金奖（第一位）等奖励。担任 卓越期刊 BMEMat（卓越期刊，IF：15.5）执行副主编、山东省医学会类器官分会第一届委 员会副主任委员、生物标志物与人工智能应用山东省工程研究中心副主任和济南市微纳传感 芯片与智能装备重点实验室主任。
教育工作经历：
1999.09-2003.07 山东大学 物理学院 学士
2003.09-2006.07 清华大学 微电子所 硕士
2006.09-2011.04 普林斯顿大学 电子工程系 博士
2011.04-2015.03 耶鲁大学 生物医学工程系 博士后
2015.04-2015.10 耶鲁大学 生物医学工程系 副研究员
2015.10-2016.05 美国 Isoplexis 公司 首席科学家
2016.06-至今 山东大学教授 海洋研究院 教授
主要荣誉：
2018-04-03 山东省杰出青年基金获得者；
2021-09-01 中国济南新动能国际高层次人才创新创业大赛一等奖；
2021-10-01 首届山东大学十大高价值应用科技成果奖；
2022-12-27 山东大学海洋研究院育人标兵；
2022-10-22 第五届“中国创翼”创业创新大赛二等奖；
2022-01-01 山东大学杰出中青年学者；
2023-09-10 山东大学优秀教师（四有好老师）提名奖；
2023-10-01 青岛市拔尖人才；
2024-06-06 山东省技术市场协会金桥奖一等奖（1/3）
2024-11-22 第十二届中国技术市场协会金桥奖一等奖（1/3）
2024-12-22 山东省科技进步二等奖（3/9））
2025-01-20 山东大学三八红旗手
2025-06-22 泰山学者特聘专家
2025-08-01 第十一届国际发明展览会金奖（1/6）
2025-09-01 山东大学“心目中的好导师”
2025-09-10 山东大学优秀研究生导师
2025-09-20 山东省优秀研究生导师
2025-11 山东省技术发明一等奖（1/15）
学术兼职：
2022-06-至今 BMEMat（卓越期刊, IF:15.5）执行副主编
2024.03-至今 Interdisciplinary Medicine（卓越期刊, IF:13.6）编委
2022.09-至今 山东省医学会类器官分会第一届委员会副主任委员
2022.08-至今 山东省医学会再生医学分会第三届委员会 委员
2020.05-至今 中国环境科学学会学术委员会委员
2023.07-至今 济南市微纳传感芯片与智能装备重点实验室主任
2022.05-至今 生物标志物与人工智能应用山东省工程研究中心副主任
2022.06-至今 青岛市政府决策咨询委员会委员
目前课题组的主要研究方向：
1、生物芯片系统在重大疾病筛查、疗效和预后评估中的应用研究：开发了蛋白分子免疫荧光芯片、miRNA 检测芯片、外泌体检测芯片、肿瘤药物高效评估 PDTF 芯片、皮肤类器官实时评估芯片等多种国际先进水平的生物芯片，在乳腺癌、卵巢癌、子宫内膜癌、结肠癌、食管癌、胃癌、心血管、抑郁症、阿尔茨海默症等 8 种重大疾病进行了~10000 例临床样本的验证，建立了重大疾病早期诊断、疗效和预后精准评估模型和临床应用方案。
2.高通量单细胞生物芯片系统在细胞治疗和疾病机制探究中的应用研究：开发了单细胞蛋白组学芯片、单细胞外泌体实时检测芯片、单细胞空间组学芯片、抗体类药物筛选单细胞评估芯片等高通量单细胞信息获取芯片，在 CAR-T 免疫细胞治疗、肿瘤组织异质性研究、单细胞高通量测序和重大疾病发生发展机制研究方面进行了大量临床验证研究。
3. 生物传感芯片在食品安全与环境监测中的应用研究：开发了 SERS 单分子检测芯片、电化学检测芯片、场效应晶体管检测芯片、纳米材料荧光转导芯片等在食品危害成份检测和海洋微生物（海底采矿区、深海生物资源）和新兴污染物检测中进行实时监测的应用验证。
1000 万元成果技术转化：
2021 年 3 月进行了肿瘤标记物检测技术（5 项专利）的成果转化，建成了国内首条超高通量条形码生物芯片的生产线，已经成功获批 2 个二类医疗器械注册证。
主持的科研项目：
1. 超高通量纳米材料抗体条形码微阵列芯片与传感器，国家重点研发计划项目课题，307.8万元，2023YFB3210401；
2. 高增敏金属纳米结构材料与聚集体生化传感器研究，国家重点研发计划项目课题，327万元，2017YFB0405401；
3. 基于高性能氧化物的柔性LTPO结构与工艺，国家重点研发计划项目课题子课题，150万元，2021YFB3600703；
4. 唾液标志物检测纳米孔SERS传感芯片系统用于抑郁症患者早期筛查，国家自然基金面上项目，50万元，62571304.
5. 用于单细胞外泌体实时分析的传感芯片研究，国家自然基金面上项目，60万元，62174101.
6. Hotspot增敏聚集体荧光生化传感器研究，国家自然基金青年项目，26万元，61701282.
7. 微纳生化传感，山东省杰出青年基金，80万元，JQ201814.
8. 基于CAR-T细胞和微纳芯片的癌症精准医疗新技术，山东省重大创新工程，130万元，2018YFJH0503.
9. 细胞制造关键技术与智能装备研发与产业化，山东省重大创新工程，300万元，2024YFJH0906；
10. 细胞治疗新技术及智能装备，山东大学青年交叉科学群体项目，700万元，2020QNQT001；
代表性学术论文（部分）：
1. Expanded InSe crystal structure with reduced intrinsic defects for high-performance fieldeffec transistors, Zhenhua Wang, Min Jin, Kepeng Song,Zonghao Wang, Zheng Zhang, Siqi Lin, Hao Ji, Mingyuan Sun, Shuai Wang, Jing Chen, Hong Liu, Yu Zhang*, Xuechao Liu*, and Lin Han*, Advanced Materials, 202506506.（影响因子：27.4)
2. Yanbo Liang, Mingyuan Sun, Chao Wang, Hongpeng Zhou, Yunhong Zhang, Xue Zhang, Miao Huang, Xiaoshuang Chen, Wei Lu, Jun Li, Hong Liu, Yu Zhang*, Lin Han*, Controllable nanopore SERS platform for single-molecule level biosensing, Coordination Chemistry Reviews, 2025, 530, 216476.（影响因子：20.3)
3. Yihe Wang, Yue Sun, Mengqi Liu, Chao Wang, Miao Huang, Jiaoyan Qiu, Ningkai Yang, Yu Zhang, Hong Liu, Lin Han*, In situ and dynamic screening of extracellular vesicles as predictive biomarkers in immune-checkpoint inhibitor therapies, Journal of Nanobiotechnology, 2025, 23, 411 (影响因子：10.6)
4. Mingyuan Sun, Zhenxiao Yu, Shuai Wang, Jiaoyan Qiu, Yuzhen Huang, Xiaoshuang Chen,
Yunhong Zhang, Chao Wang, Xue Zhang, Yanbo Liang, Hong Liu, Qunxin She, Yu Zhang* and Lin Han*, Universal Amplification-Free RNA Detection by Integrating CRISPR-Cas10 with Aptameric Graphene Field-effect Transistor, Nano-Micro Letters, 2025, 17, 242. (影响因子：31.6)
5. Jing Chen, Junqiang Zhu, Ping Li, Jiaoguo Hu, Qiuliang Li, Zhen-hua Wang, Zheng Wang, Hengji Li, Siqi Lin, Xiaofei Yue, Tian-Ling Ren, Hong Liu, Min Jin*, and Lin Han*, Nano Letters, 2025, 25, 13909.
6. Chao Wang, Yunrui Han, Yihe Wang, Mingyuan Sun, Yanbo Liang, Miao Huang, Yu Yang, Huili Hu, Yu Zhang, Lin Han*, Single-cell isolation chip integrated with multicolor barcode array for high-throughput single cell exosomes profiling in tissue samples, Advanced Materials, 2025,37(5), 2411259.（影响因子：27.4)
7. He Xia, Wenjuan Zhou, Dezheng Li, Fan Peng, Chao Wang, Liyang Yu, Jingyi Du, Yang Zheng, Yuanhua Sang, Yu Zhang, Lin Han*, Hong Liu*, Aijun Hao*, Jichuan Qiu*, Engineering Neural Stem Cells with Micropatches for Improved Therapy of Traumatic Brain Injury. Angewandte Chemie International Edition, 2025, 64, e202512804. (影响因子：16.9)
8. Xue Zhang, Yibin Jia, Zhikai Li, Yunhong Zhang, Chao Wang, Yanbo Liang, Jiaoyan Qiu, Mingyuan Sun, Xiaoshuang Chen, Miao Huang, Yu Zhang, Jianbo Wang, Hong Liu, Chuanbin Mao, Lin Han, Microfluidic Biochip-Based Multiplexed Profiling of Small Extracellular Vesicles Proteins Integrated with Machine Learning for Early Disease Diagnosis, Advanced Science, 2025, e06167. (影响因子：14.3).
9. Wang Chao, Miao Huang, Junxia Han, Mingyuan Sun, Haijun Li, Yu Zhang, Hong Liu, Lin Han, Stereo-cell: A planar DNA nanoball-array route to ultrahigh-throughput, imaging-integrated single-cell profiling, BMEMat, 2025, e70035. (影响因子：15.5)
10. Jiaoyan Qiu, Yu Wu, Yihe Wang, Chao Wang, Soo-Yeon Cho, Hui Huang, Yu Zhang, Lin Han, High-throughput exosomes analysis for ovarian cancerscreening based on a double-positive surface markerdetection biochip, BMEMat, 2025, e70015. (影响因子：15.5)
11. Mingyuan Sun, Shuai Wang, Yanbo Liang, Chao Wang, Yunhong Zhang, Hong Liu, Yu Zhang*，Lin Han* ， Flexible graphene field-effect transistors and their application in flexible biomedical sensing, Nano-Micro Letters, 2024, 34. (影响因子：31.6)
12. Jing Chen, Ming-Yuan Sun, Zhen-Hua Wang, Zheng Zhang, Kai Zhang, Shuai Wang, Yu Zhang, Xiaoming Wu, Tian-Ling Ren*, Hong Liu, Lin Han*, Performance Limits and Advancements in Single 2D Transition Metal Dichalcogenide Transistor, Nano-Micro Letters, 2024, 16(264). (影响因子：31.6)
13. Jiaoyan Qiu，Yanbo Liang, Chao Wang, Yang Yu, Yu Zhang, Hong Liu, Lin Han*，Microfluidic Barcode Biochips for High-Throughput Real-Time Biomolecule and Single-Cell Screening，Engineering, 2024, doi.org/10.1016/j.eng.2024.06.016. (影响因子：10.1)
14. Yunrui Han, Guangpeng Fan, Yingkuan Han, Xin Huang, Weifeng Wang, Xiaoming Luo, Yu Zhang, Lin Han*, Suppression of coffee rings by controllable nanoparticle enrichment through superhydrophobicity-enabled dynamic evaporation, Journal of Colloid and Interface，2024, 673,735-745. (影响因子：9.4)
15. Mengqi Liu, Yihe Wang, Chao Wang, Ping Li, Jiaoyan Qiu, Ningkai Yang, Mingyuan Sun, and Lin Han*, A Microfluidic 3D-Tumor-Spheroid Model for the Evaluationof Targeted Therapies from Angiogenesis-Related Cytokines at the Single Spheroid Level, Advanced Healthcare Materials, 2024, 2402321. (影响因子：10.3)
16. Chao Wang, Jiaoyan Qiu, Mengqi Liu, Yihe Wang, Yang Yu, Hong Liu, Yu Zhang,* and Lin Han*，Microfluidic Biochips for Single-Cell Isolation and Single-Cell Analysis of Multiomics and Exosomes, Advanced Science, 2024, 2401263, DOI: 10.1002/advs.202401263. (影响因子：14.3)
17. Mingyuan Sun , Yunhong Zhang , Shuai Wang, Shun Wang, Liang Gao , Meng Guo , Hong Liu, Lin Han* , Yu Zhang*，Laser-induced graphene van der Waals contact-enabled highperformance 2D-materials-based field-effect transistor, Carbon, 2024, 225119151. (影响因子：10.5)
18. Mingyuan Sun, Congcong Zhang*, Shan Lu, Shahid Mahmood, Jian Wang, Chunhui Sun, Jinbo Pang, Lin Han*, Hong Liu*, Recent advances in graphene field-effect transistor toward biological detection, Advanced Functional Materials, 2024, 2405471. (影响因子：18.5)
19. Hongpeng Zhou , Jiaoyan Qiu , Yunhong Zhang , Yanbo Liang , Lin Han * , Yu Zhang * ，Selfassembled C-Ag hybrid nanoparticle on nanoporousGaN enabled ultra-high enhancement factor SERS sensor for sensitive thiram detection , the Journal of Hazardous Materials, 2024,469, 133868. (影响因子：12.2)
20. Jiaoyan Qiu , Qindong Guo , Yujin Chu , Chunhua Wang , Hao Xue , Yu Zhang, Hong Liu, Gang Li, Lin Han*, Efffcient EVs separation and detection by an alumina-nanochannel-arraymembrane integrated microffuidic chip and an antibody barcode biochip，Analytical Chimica Acta, 2024, 1304342576. (影响因子：6.558)
21. Yujuan Zhao, Jiaoyan Qiu , Peiqing Jian , Min Wang , Mingyuan Sun , Guangpeng Fan , Ningkai Yang , Ning Huang , Yunrui Han, Lin Han* , Yu Zhang*，RNA extraction-free reduced graphene oxide-based RT-LAMP ffuorescence assay for highly sensitive SARS-CoV-2 detection，Talanta, 2024, 227, 126413. (影响因子：5.6)
22. Chao Wang, Chunhua Wang, Huimin Liu, Songbo Zhao, Jiaoyan Qiu, Ping Li, Zhongqian Liu, Mingyuan Liu, Xiaowei Shao, Yihe Wang, Xiaohong Liang, Lifen Gao, Chunhong Ma, Wei Song, Yu Zhang, Lin Han*, Immune function assessing of TIM3/CD28-modified CD19 CAR-T cells and general CD19 CAR-T cells through a highthroughput single-cell microarray platform,Interdisciplinary Medicine, 2023, DOI: 10.1002/INMD.20230030. (即时影响因子：～12)
23. Chengming Lou, Hongru Yang, Ying Hou, Haina Huang, Jichuan Qiu, Chunhua Wang*Yuanhua Sang*, Hong Liu*, and Lin Han*, Microfluidic platforms for real-time in situ monitoring for biomarers for cellular processes, Advanced Materials, 2023,2307051. (影响因子：27.4)
24. Jing Chen, Xue-Chun Zhao, Ye-Qing Zhu, Zheng-Hua Wang, Zheng Zhang, Ming-Yuan Sun, Shuai Wang, Yu Zhang, Lin Han*, Xiao-Ming Wu*, Tian-Ling Ren*, Polarized Tunneling Transistor for Ultralow-Energy-Consumption Artificial Synapse toward Neuromorphic Computing, ACS Nano, 2024,18(1), 581-591. (影响因子：15.8)
25. Jing Chen, Ye-Qing Zhu, Xue-Chun Zhao, Zheng-Hua Wang, Kai Zhang, Zheng Zhang, MingYuan Sun, Shuai Wang, Yu Zhang, Lin Han*, Xiaoming Wu*, and Tian-Ling Ren*, PZT-Enabled MoS2 Floating Gate Transistors: Overcoming Boltzmann Tyranny and Achieving Ultralow Energy Consumption for High-Accuracy Neuromorphic Computing, Nano Letters, 2023, 23, 10196–10204. (影响因子：9.6)
26. Ping Li, Chao Wang, Jiaoyan Qiu, Fangteng Song, Yuzhen Huang, Yunhong Zhang, Kai Zhang, Hao Ji, Yuanhua Sang, Jonny J. Blaker, Yu Zhang, Lin Han*, Inhibitory effect of zinc oxide nanorod arrays on breast cancer cells profiled through real-time cytokines screening by a single-cell microfluidic platform, BMEmat, 2023, 1(3), 1-16 (影响因子：15.5)
27. Yuzhen Huang, Kai Zhang, Xiaoshuang Chen, Xiaohui Yan, Jiaoyan Qiu, Yu Zhang *, Lin Han*, Enhanced dual-mode electrochemical zinc ion sensing by electric field-driven bi-directional mass transport, Chemical Engineering Journal，2023, 475, 146258. (影响因子：13.3)
28. Hao Ji, Zhenhua Wang, Shun Wang, Chao Wang, Yujin Chu, Hong Liu, Yu Zhang*, Lin Han*, A novel InSe-FET biosensor based on carrier-scattering regulation derived from the DNA probe assembly-determined electrostatic potential distribution, Advanced Functional Materials, 2023, 33(14), 2213277. (影响因子：18.5)
29. Qihang He, Jiaoyan Qiu, Yingkuan Han, Min Wang, Yu Zhang*, Lin Han*, Ag@C decorated GaN nanoflower enabled super-stable, single molecule level SERS substrate integrated with machine learning for multiple analytes identification, Materials Today Nano, 2023, 22,100305. (影响因子：10.3)
30. Yuzhen Huang, Xiaohui Yan, Qihang He, Jiaoyan Qiu, Yu Zhang*, Lin Han*, Ceria and gold codecorated porous MoS2@graphene nanocomposite electrochemical electrode integrated with smartphone-controlled microstation for simultaneous dual metal ions detection, Electrochimica Acta, 2023, 437: 141509. (影响因子：7.336)
31. Shun Wang, Mingyuan Sun, Yunhong Zhang, Hao Ji, Jianwei Gao, Shuai Song, Jun Sun, Hong Liu, Yu Zhang* and Lin Han*, Ultrasensitive antibiotic perceiving based on aptamerfunctionalized ultraclean graphene field-effect transistor biosensor, Analytical Chemistry, 2022, 94(42), 14785-14793. (影响因子：8.008)
32. Jiaoyan Qiu，Yujin Chu, Qihang He, Yingkuan Han, Yu Zhang,* and Lin Han*, A self-assembly hydrophobic oCDs/Ag nanoparticles SERS sensor for ultrasensitive melamine detection in milk, Food Chemistry, 2023,402:134241. (影响因子：8.5)
33. Di Huang, Yujin Chu, Jiaoyan Qiu, Xiaoshuang Chen, Junhua Zhao, Yu Zhang, Shunjia Li, Yufeng Cheng, Han Shi, Lin Han*, Jianbo Wang*, a novel diagnostic signature of circulating tsRNAs and miRNAs in esophageal squamous cell carcinoma detected with a microfluidic platform, Analytica Chimica Acta, 2023, 1272, 341520. (影响因子：6.558)
34. Min Wang, Yujuan Zhao, Xuewen He, Ben Zhong Tang, Hong Liu, Yu Zhang*, Lin Han*, A sensitive fluorescence assay based on aggregation-induced emission by copper-free click reaction for rapid ctDNA detection, Talanta, 2023, 259, 124562. (影响因子：5.6)
35. Xiaowei Shao, Zhongqian Liu, Shijie Mao and Lin Han*，Unravel the Mechanobiology Underlying Traumatic Brain Injury with Advanced Technologies and Biomaterials，Advanced Healthcare Materials, 2022, 2200760. (影响因子：10.3)
36. Fangteng Song, Chao Wang, Chunhua Wang, Jianbo Wang, Yu Wu, Yihe Wang, Hong Liu,* Yu Zhang,* and Lin Han*，Multi-Phenotypic Exosome Secretion Profiling Microfluidic Platform for Exploring Single-Cell Heterogeneity，Small Methods, 2022, 2200717. (影响因子：10.7)
37. Chao Wang, Chunhua Wang, Yu Wu, Jianwei Gao, Yingkuan Han, Yujin Chu, Le Qiang, Jiaoyan Qiu, Yakun Gao, Yanhao Wang, Fangteng Song, Yihe Wang, Xiaowei Shao, Yu Zhang*, and Lin Han*, High-Throughput, Living Single-Cell, Multiple Secreted Biomarker Profiling Using Microfluidic Chip and Machine Learning for Tumor Cell Classification, Advanced Healthcare Materials, 2022, 11(13), 202102800. (影响因子：10.3)
38. Zhijie Guo, Chunhui Sun*, Hongru Yang, Haoyang Gao, Na Liang, Jian Wang, Shuang Hu, Na Ren, Jinbo Pang, Jingang Wang, Ning Meng*, Lin Han*, and Hong Liu*，Regulation of Neural Differentiation of ADMSCs using Graphene-Mediated Wireless-Localized Electrical Signals Driven by Electromagnetic Induction, Advanced Science, 2022, 9(14), 2104424. (影响因子：14.3)
39. Jiaoyan Qiu, Peiqing Jiang, Chunhua Wang, Yujin Chu, Yu Zhang, Mei Zhang, Lin Han*, LysAuNPs@MoS2 nanocomposites self-assembled microfluidic immunoassay biochip for the ultrasensitive detection of multiplex biomarkers for cardiovascular diseases, Analytical Chemistry, 2022, 94（11）：4720-4728. (影响因子：8.008)
40. Yingkuan Han, Yunrui Han, Yuzhen Huang, Chao Wang, Hong Liu, Lin Han* and Yu Zhang*，Laser-induced graphene superhydrophobic surface transition from pinning to rolling for multiple applications, Small Methods, 2022, 202200096. (影响因子：10.7)
41. Jianwei Gao, Chunhua Wang, Chao Wang, Yujin Chu, Shun Wang, Mingyuan Sun, Hao Ji, Yankun Gao, Yanhao Wang, Yingkuan Han, Fangteng Song, Hong Liu, Yu Zhang*, Lin Han*, Poly-L-Lysine-modified graphene field-effect transistor biosensor for ultrasensitive breast cancer miRNAs and SARS-CoV-2 RNA detection, Analytical Chemistry, 2022 Jan 25; 94(3): 1626–1636. (影响因子：8.008)
42. Yunrui Han, Yingkuan Han, Jiayang Sun, Hong Liu, Yu Zhang*, Lin Han*, Controllable nanoparticle aggregation through superhydrophobic laser-induced graphene dynamic system for surface-enhanced Raman scattering detection, ACS Applied Materials & Interfaces, 2022, 14， 3504-3514，https://doi.org/10.1021/acsami.1c21159 (影响因子：10.1)
43. Yihe Wang, Mengqi Liu, Yu Zhang, Hong Liu, Lin Han*, Recent methods of droplet microfluidics and their applications in spheroids and organoids, Lab on a Chip, 2023,23(5):1080-1096, doi: 10.1039/d2lc00493c. (影响因子：6.12)
44. Yuzhen Huang, Ping Li, Yingkuan Han, Yu Zhang*, and Lin Han*, Controllable surface engineered three-dimensional porous graphene-based electrode for ultrasensitive flexible electrochemical sensing, Applied Surface Science, 2022, 604:154530. (影响因子：6.3)
45. Yuzhen Huang, Yingkuan Han, Jiayang Sun, Yu Zhang*, Lin Han*, Dual nanocatalysts codecorated three-dimensional, laser-induced graphene hybrid nanomaterials integrated with a smartphone portable electrochemical system for point-of-care non-enzymatic glucose diagnosis, Materials Today Chemistry, 2022, 24:100895. (影响因子：6.7)
46. Ranran Xu, Yongqiang Cheng*, Xiaotong Li, Ziwei Zhang, Meijia Zhu, Xiaoxiao Qi, Longyu Chen, Lin Han*, Aptamer-based signal amplification strategies coupled with microchips for highsensitivity bioanalytical applications: a review, Analytica Chimica Acta, 2022,
https://doi.org/10.1016/j.aca.2022.339893. (影响因子：6.558)
47. Jianwei Gao, Chunhua Wang, Yujin Chu, Yingkuan Han, Yakun Gao, Yanhao Wang, Chao Wang, Hong Liu, Lin Han*, Yu Zhang*, Graphene oxide-graphene Van der Waals heterostructure transistor biosensor for SARS-CoV-2 protein detection, Talanta, 2022, 240:123197. (影响因
子：5.6)
48. Ying Kong, Jiazhi Duan, Feng Liu, Lin Han*, Gang Li, Chunhui Sun, Yuanhua Sang*, Shuhua Wang, Fan Yi* and Hong Liu*, Regulation of stem cell fate using nanostructure-mediated physical signals, Chemical Society Reviews, 2021,50, 12828-12872. (影响因子：40.4)
49. Xiaowei Shao, Chunhua Wang, Chao Wang, Lei Han, Yunrui Han, Dean Nizetic, Yu Zhang*, and Lin Han*, Mechanical stress induces a transient suppression of cytokine secretion in astrocytes assessed at the single-cell level with a high-throughput microfluidic chip, Advanced Healthcare Materials, 2021, 2100698. (影响因子：10.3)
50. Ying Kong, Feng Liu, Baojin Ma, Jiazhi Duan, Wenhu Yuan, Yuanhua Sang, Lin Han*, Shuhua Wang*, and Hong Liu*, Wireless localized electrical stimulation generated by an ultrasounddriven piezoelectric discharge regulates proinflammatory macrophage polarization, Advanced Science, 2021, 2100962(1-12). (影响因子：14.3)
51. Yanhao Wang, Jinbo Pang*, Qilin Cheng, Lin Han*, Yufen Li, Xue Meng, Bergoi Ibarlucea, Hongbin Zhao, Feng Yang, Haiyun Liu, Hong Liu*, Weijia Zhou, Xiao Wang, Mark H. Rummeli, Yu Zhang*, Gianaurelio Cuniberti, Applications of 2D Layered Palladium Diselenide and its van
der Waals Heterostructures in Electronics and Optoelectronics. Nano-Micro Letters. 2021, 13(1):143. (影响因子：31.6)
52. Qihang He, Yingkuan Han, Yuzhen Huang, Jianwei Gao, Yakun Gao, Lin Han*, Yu Zhang*, Reusable dual-enhancement SERS sensor based on graphene and hybrid nanostructures for ultrasensitive lead (II) detection, Sensors and Actuators: B. Chemical, 2021, 341, 130031. (影
响因子：8.0)
53. Fagnteng Song, Chao Wang, Chunhua Wang, Jianwei Gao, Hong Liu, Yu Zhang*, Lin Han*, Enrichment-detection integrated exosome profiling biosensors promising for early diagnosis of cancer, Analytical Chemistry, 2021, 93, 11, 4697–4706. (影响因子：8.008)
54. Yujin Chu, Yakun Gao, Wei Tang, Le Qiang, Yingkuan Han, Jianwei Gao, Yu Zhang, Hong Liu, Lin Han*, Attomolar-level ultrasensitive and multiplex miRNA detection enabled by a nanomaterials locally assembled microfluidic biochip for cancer diagnosis, Analytical Chemistry, 2021, 93, 12, 5129–5136. (影响因子：8.008)
55. Yanhao Wang, Yunhong Zhang, Qilin Cheng, Jinbo Pang, Yujin Chu, Hao Ji, Jianwei Gao, Yingkuan Han, Lin Han*, Hong Liu*, Yu Zhang*, Large area uniform PtSx synthesis on sapphire substrate for performance improved photodetectors, Applied Materials Today, 2021, 25, 101176. (影响因子：7.2)
56. Chunhua Wang, Yu Zhang*, Wei Tang, Chao Wang, Yingkuan Han, Le Qiang, Jianwei Gao, Hong Liu, Lin Han*, Ultrasensitive, high-throughput and multiple cancer biomarkers simultaneous detection in serum based on graphene oxide quantum dots integrated microfluidic biosensing platform, Analytica Chimica Acta, 2021, 1178:338791. (影响因子：6.558)
57. Chunhua Wang, Chao Wang, Jiaoyan Qiu, Jianwei Gao, Hong Liu, Yu Zhang*, Lin Han*, Ultrasensitive, high-throughput, and rapid simultaneous detection of SARS-CoV-2 antigens and IgG/IgM antibodies within 10 min through an immunoassay biochip, Microchimica Acta, 2021, 188:262. (影响因子：6.408)
58. Yakun Gao, Yingkuan Han, Chao Wang, Le Qiang, Jianwei Gao, Yanhao Wang, Hong Liu, Lin Han*, Yu Zhang*, Rapid and sensitive triple-mode detection of causative SARS-CoV-2 virus specific genes through interaction between genes and nanoparticles, Analytica Chimica Acta, 2021, 1154, 338330 (1-11). (影响因子：6.558)
59. Yuzhen Huang, Yingkuan Han, Yakun Gao, Jianwei Gao, Hao Ji, Qihang He, Jianbo Tu, Guanqiu Xu, Yu Zhang*, Lin Han*, Electrochemical sensor array with nanoporous gold nanolayer and ceria@gold corona-nanocomposites enhancer integrated into microfluidic for simultaneous ultrasensitive lead ion detection, Electrochimica Acta, 2021, 373, 137921(1-8). (影响因子：7.336)
60. Jianfeng Jiang, Fanqi Meng, Qilin Cheng, Aizhu Wang, Yuke Chen, Jie Qiao, Jinbo Pang, Weidong Xu, Hao Ji, Yu Zhang, Qinghua Zhang, Shanpeng Wang, Xianjin Feng, Lin Gu, Hong Liu*, and Lin Han*, Low Lattice Mismatch InSe-Se Vertical Van der Waals Heterostructure for High-performance Transistors via Strong Fermi-level Depinning, Small Methods, 2020, 4（8），202000238. (影响因子：10.7)
61. Fulei Wang，Jianfeng Jiang, Qilu Liu, Yu Zhang, Jianjun Wang, Shuhua Wang, Lin Han*, Hong Liu*, Yuanhua Sang*, Piezopotential gated two-dimensional InSe field-effect transistor for designing a pressure sensor based on piezotronic effect, Nano Energy, 2020, Jan. 70:104457.(影响因子：16.8)
62. Yanhao Wang, Jianwei Gao, Bin Wei, Yingkuan Han, Chao Wang, Yakun Gao, Hong Liu*, Lin Han*, Yu Zhang*, Reduction of the ambient effect in multilayer InSe transistors and a strategy toward stable 2D-based optoelectronic applications, Nanoscale, 2020,12, 18356-18362. (影响因子：8.3)
63. Han, Yingkuan; Qiang Le, Gao Yakun, Gao Jianwei, He Qihang, Liu Hong, Han, Lin*
Zhang, Yu*. Large-area surface-enhanced Raman spectroscopy substrate by hybrid porous GaN with Au/Ag for breast cancer miRNA detection. Applied Surface Science. 2020, 541:148456. (影响因子：6.3)
64. Min Hao, Jianlong He, Chunhua Wang, Chao Wang, Baojin Ma, Shan Zhang, Jiazhi Duan, Feng Liu, Yu Zhang, Lin Han*, Hong Liu*, and Yuanhua Sang*, Effect of hydroxyapatite nanorods on the fate of human adipose-derived stem cells assessed in Situ at the single cell level with a high-throughput, real-time microfluidic chip, Small, 2019,15(51):1905001. (影响因子：13)
65. Jianfeng Jiang, Qinghua Zhang, Aizhu Wang, Yu Zhang, Fanqi Meng, Congcong Zhang, Xianjin Feng, Yuanping Feng, Lin Gu*, Hong Liu*, and Lin Han*，A Facile and Effective Method for Patching Sulfur Vacancies of WS2 via Nitrogen Plasma Treatment ， Small, June 18,2019 ,15(36): 1901791. (影响因子：13)
66. Jianfeng Jiang, Jingxin Li, Yutao Li, Jiazhi Duan, Linshen Li, Ye Tian, Zhihua Zong, Haotian Zheng, Xianjin Feng, Qiqiang Li, Hong Liu, Yu Zhang*, Tian-ling Ren*, Lin Han*，Stable InSe Transistors with High-field Effect Mobility for Reliable Nerve Signal Sensing ，Npj 2D Materials and Applications, July 4, 2019, 3:29. (影响因子：10.51)
周伟家
周伟家，男，1982年生，济南大学前沿交叉科学研究院，副院长，教授，博士生导师，学术带头人。主要从事电催化和微纳器件研究，在电催化剂催化位点调控和全解水系统优化方面取得一系列研究成果，以第一或通讯作者在EnergyEnviron. Sci. 、Angew. Chem. Int. Ed.、ACS Nano等期刊发表SCI收录论文76篇其中IF大于15的21篇，被他引7126次，H因子39，中国百篇最具影响力国际学术论文1篇，ESI高被引用论文12篇，2018年“全球高被引科学家”(交叉学科) ;主持“国家优秀青年基金”(2020)“泰山学者青年专家计划”(2019) 和“广东省自然科学杰出青年基金”(2017)等国家省部级项目11项。申请发明专利20余项，2019年获得山东省自然科学-等奖(第三位)。
